When should resuscitation be ceased in cases of PEA/asystole?

Resuscitation in cases of pulseless electrical activity (PEA) or asystole should typically be considered for cessation after 30 to 45 minutes of advanced life support interventions if there is no sign of reversible causes or response to treatment. This duration reflects current best practices that balance the need for effective resuscitation efforts with the understanding that prolonged attempts may not lead to a successful outcome if there are no indications of potential reversibility, such as clear identification and management of contributing factors that could be addressed.

In patients with PEA or asystole, advanced life support measures—such as high-quality CPR and appropriate use of medications—may improve the chances of recovery if they are effective. If there is an absence of any response from the patient within the specified timeframe, it suggests a need to evaluate the effectiveness of the resuscitation efforts and the potential futility of further intervention without any observable change in the patient's condition.

Shorter durations for ceasing resuscitation efforts, such as after 10 minutes with a witness present or any decision to cease solely based on expectations of response without a thorough assessment of reversible causes, do not sufficiently allow for the complexity of these cases. Additionally, the option suggesting a cessation of resuscitation